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活性蛋白
- Recombinant Human CD44 antigen(CD44),partial (Active)
- 恒遠(yuǎn)生物蛋白表達(dá)平臺建立了從原核到真核四大重組表達(dá)系統(tǒng),并建立無細(xì)胞表達(dá)系統(tǒng),擁有基于昆蟲病毒外膜蛋白展示的蛋白表達(dá)技術(shù)、膜蛋白表達(dá)技術(shù)等一系列蛋白表達(dá)及純化技術(shù),有能力制備各種高難度蛋白。
Recombinant Human CD44 antigen(CD44),partial (Active)
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貨號：HYB-10152
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規(guī)格：
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圖片：
產(chǎn)品詳情
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純度：Greater than 90% as determined by SDS-PAGE.
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內(nèi)毒素：Less than 1.0 EU/ug as determined by LAL method.
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生物活性：Measured by its binding ability in a functional ELISA. Immobilized CD44 at 2 μg/ml can bind Anti-CD44 mouse monoclonal antibody(CSB-MA004938A0m, antigen from E.coli), the EC50 of the CD44 protein is 11.89-14.94 ng/ml.
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基因名：CD44
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別名：LHR; BA-1; CD 44; CD44; CD44 antigen; CD44 molecule (Indian blood group); CD44 molecule; CD44_HUMAN; CDw44; CDW44 antigen; Cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMR-III; Epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HSA; HUTCH-I; HUTCH1; HUTCHI; Hyaluronate receptor; IN; INLU-related p80 Glycoprotein; MC56; MDU2; MDU3; MGC10468; MIC4; MUTCH I; MUTCH1; PGP-1; PGP-I; PGP1; Phagocytic glycoprotein 1; Phagocytic glycoprotein I; Soluble CD44
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分子結(jié)構(gòu)：
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種屬：Homo sapiens (Human)
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蛋白長度：Partial
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來源：Mammalian cell
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分子量：50.98 kDa
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表達(dá)區(qū)域：21-220aa
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氨基酸序列QIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIP
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蛋白標(biāo)簽：C-terminal hFc-tagged
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產(chǎn)品提供形式：Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
緩沖液：Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4
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儲存條件：Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質(zhì)期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事項：Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
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產(chǎn)品描述：
The Recombinant Human CD44 Antigen (CD44) is produced in mammalian cells. The CD44 protein (21-220AA) in which a part extracellular domain was encoded by its DNA sequence and this protein carried a human Fc fragment at the C-terminus. CD44 is a surface glycoprotein that plays a part in cell-to-cell interactions, cell proliferation, angiogenesis, and many other cellular activities.
The Recombinant CD44 antigen finds uses in studies on different forms of cancer. This antigen’s role in cellular proliferation, invadopodia formation, cellular survival, and metastasis is of importance in studying different forms of cancer.
By acting on ligands such as hyaluronan, osteopontin, and collagen, CD44 activates various cancer-related pathways. Of such pathways are the NF-kB pathway, RhoGTPases pathway, and the PI3K/AKT pathway. The Recombinant Human CD44 has a molecular weight of 51 kDa and purity over 85% on SDS-PAGE. Its functionality is ELISA-validated and its identity is verified with LC-MS/MS Analysis. -
Datasheet & COA：Please contact us to get it.
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